Background: Higher dietary fibre intakes are associated with a reduced risk of developing cardiovascular disease (CVD), and increasing intake has been shown to reduce blood pressure and other cardiometabolic risk factors. The extent to which dietary fibre can further reduce risk for those with CV...

Background: Fibre is promoted as part of a healthy dietary pattern and in diabetes management. We have considered the role of high-fibre diets on mortality and increasing fibre intake on glycaemic control and other cardiometabolic risk factors of adults with prediabetes or diabetes. Methods an...

Aim: To determine whether higher fibre intakes during childhood or adolescence effect a broad range of intermediate markers of cardiometabolic risk or other health related issues. Materials and methods: We used online searches up to January 2020 and manual searches to identify prospective obse...

Background: Cardiovascular disease (CVD) risk factors are associated with low serum 25 hydroxyvitamin D (25(OH)D) concentrations in observational studies; however, clinical trial findings are inconsistent. Objective: We assessed the effect of vitamin D supplementation and increased serum 25(OH)D ...

CONTEXT: Controlling diabetes, a worldwide metabolic disease, by effective alternative treatments is currently a topic of great interest. Camel milk is believed to be a suitable hypoglycemic agent in experimental animals and patients with diabetes. The current systematic review aimed at evaluatin...

Data on diet-genotype interactions in the prevention or treatment of dyslipidemia have increased remarkably. This systematic review aimed to assess nutrigenetic studies regarding the modulating effect of diet on cholesteryl ester transfer protein (CETP) polymorphisms in relation to metabolic trai...

BACKGROUND: Micronutrient deficiency is one of the major public health problems in the Middle East affecting economic, political and social development of countries. The three commonest micronutrient deficiencies belong to iron, iodine and vitamin A. METHODS: we conducted a systematic review of p...

OBJECTIVES: The role of vitamin D deficiency has been linked with recurrent upper respiratory tract infections, but its impact on the frequency of tonsillitis is not yet fully understood. The objective of this study is to determine the association between vitamin D deficiency and recurrent tonsil...

运用网状Meta分析方法系统评价口服酸枣仁类中成药治疗原发性失眠症的疗效。计算机检索CNKI、Wanfang、VIP、CBM、PubMed、EMbase、Web of Science、Medline、Cochrane Library数据库，检索时间为建库至2020年8月，按照预先设定的纳入、排除标准，筛选口服酸枣仁类中成药单用或联合常规镇静催眠药治疗原发性失眠症的随机对照试验。由2名研究者独立筛选文献、提取资料并评价纳入研究的偏倚风险后，采用Stata 15.0和R软件进行传统Meta和贝叶斯网状Meta分析。最终纳入42个RCTs,涉及9种口服中成药，4 196例患者。Meta分析结果...

背景与目的 目前，失眠症的治疗主要包括镇静催眠药和认知行为治疗（CBT）。镇静催眠药可 迅速缓解失眠症状、起效快、短期应用疗效佳等优势，但是长期应用存在认知功能损 害、药物依赖、停药反跳等不良影响。大量研究显示，CBT 短期治疗(4-8 周)疗效不亚 于镇静催眠药，长期治疗无认知损害、药物依赖等不良反应且疗效更为持久，CBT 为 当前失眠症治疗的首选疗法。CBT 主要包括刺激控制疗法、睡眠限制疗法、睡眠卫生 教育、认知治疗和放松疗法等。然而，在临床工作中，传统面对面 CBT 的实施并不广 泛，并非由于其疗效问题，而是受到治疗周期长、花费高、治疗师缺乏以及地域等因 素的限制，使治疗不能完整...