OBJECTIVE: The objective of this study was to investigate the effect of probiotics on functional abdominal pain disorders (FAPD) and functional constipation (FC). METHODS: A systematic review was conducted, searching PubMed and Cochrane databases from inception to January 2018 for randomized cont...

Objective: Asystemized approach tosubjective cognitive complaints (SCCs) in elderly people isneeded owing tothehighprevalence ofsuchcomplaints andtheir impact onthepsychosocial well‐being ofthose affected. Theaimofthisstudy was tocarry outasystematic review ofthecharacteristics andeffectiveness o...

CONTEXT: Parents whose infants are being treated in the NICU are at high risk for depression and anxiety, with negative implications for parenting and infant development. OBJECTIVE: We conducted a systematic review and meta-analysis of NICU-based interventions to reduce maternal depressive or anx...

Background: Childhood-onset systemic lupus erythematosus (cSLE) is a complex multisystem autoimmune disease often associated with pain, fatigue, and mood-related disturbances. cSLE is associated with increased disease severity and higher rates of mortality as compared to adult onset SLE. Therefor...

BACKGROUND & AIMS: Epidemiological studies show inconsistent findings on the association of dietary fiber intake with risk of metabolic syndrome (MetS). Herein, we aim to conduct a meta-analysis of published studies to determine the role of dietary fiber in prevention of MetS. METHODS: A systemat...

Results of the relationships between dietary whole-grain consumption and the risk of all-cause, CVD and cancer-specific mortality are mixed. We summarised the evidence based on a meta-analysis of prospective cohort studies. Pertinent studies were identified by searching articles in the MEDLINE an...

Background: Cardiovascular disease is associated with oxidative stress, inflammatory processes, and vascular dysfunction. Lycopene, a carotenoid found in tomatoes, is an antioxidant with a protective effect on lipid peroxidation and anti-atherosclerotic capacity. This review summarises current ev...

Background: Vitamin C (ascorbic acid) seems to attenuate the overproduction of reactive species during and after exercises. Yet, no meta-analysis has summarized the magnitude of this effect. The objective of this study was to systematically review the effects of vitamin C supplementation on oxida...

Background: Vitamin D deficiency is highly prevalent in children with inflammatory bowel disease (IBD). This may contribute to an increased risk of poor bone health and may also influence the course of disease. An optimal treatment strategy of vitamin D therapy in children with IBD has not yet be...

Little is known on the effect of sodium intake on BP of children with clinical conditions. Our objective was therefore to review systematically studies that have assessed the association between sodium intake and BP in children with various clinical conditions. A systematic search of several data...