作者:Kayoko Hashimoto
关键词:atopic dermatitis; meta-analysis; psychological and educational interventions; systematic review
发表时间:2017
发表期刊:Behaviour Change
证据类型:系统评价/Meta分析
Psychological and educational interventions are valuable adjuncts in the manage- ment of adult atopic dermatitis. We performed a systematic review and meta-analysis of randomised controlled trials (RCTs) of the efficacy of these interventions. Twelve articles published between 1986 and 2013 were identified through elec- tronic searches. The methodological quality was assessed according to the Cochrane Handbook for Systematic Reviews of Interventions, version 5.1.1 (Higgins & Green, 2015). A random-effects model was used to estimate the standardised mean differ- ence (SMD). No significant difference was found in eczema severity determined in three RCTs (124 participants; SMD, -0.29; 95% CI [-0.64, 0.07]) and dropout rate in five RCTs (198 participants; relative risk, 0.66; 95% CI [0.20, 2.17]). Educa- tion via online video was significantly superior to handouts in ameliorating eczema severity in one RCT (80 participants). We conclude that, rather than a combina- tion of these interventions with conventional therapy being of no value, the data did not have sufficient power to provide evidence-based conclusions.