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Systematic review: the effects of carbonated beverages on gastro-oesophageal reflux disease

作者:Johnson, T.; Gerson, L.; Hershcovici, T.; Stave, C.; Fass, R.

关键词:*Carbonated Beverages/adverse effects; Gastric Emptying/*physiology; Gastroesophageal Reflux/*complications/physiopathology; Humans; Manometry; Beverages; Carbonated Beverages; Gastroesophageal Reflux

发表时间:2010

发表期刊:ALIMENTARY PHARMACOLOGY & THERAPEUTICS

证据类型:系统评价/Meta分析

BACKGROUND: Carbonated beverages have unique properties that may potentially exacerbate gastro-oesophageal reflux disease (GERD), such as high acidity and carbonation. Cessation of carbonated beverage consumption is commonly recommended as part of lifestyle modifications for patients with GERD. AIMS: To evaluate the relationship of carbonated beverages with oesophageal pH, oesophageal motility, oesophageal damage, GERD symptoms and GERD complications. METHODS: A systematic review. RESULTS: Carbonated beverage consumption results in a very short decline in intra-oesophageal pH. In addition, carbonated beverages may lead to a transient reduction in lower oesophageal sphincter basal pressure. There is no evidence that carbonated beverages directly cause oesophageal damage. Carbonated beverages have not been consistently shown to cause GERD-related symptoms. Furthermore, there is no evidence that these popular drinks lead to GERD complications or oesophageal cancer. CONCLUSIONS: Based on the currently available literature, it appears that there is no direct evidence that carbonated beverages promote or exacerbate GERD.