Depression is the most prevalent mental health problem among older adults. Exercise has been found to have a protective and treatable effect on depression in this population. A systematic review of literature published between 2006 and 2015 was performed to examine the influence of exercise interventions in reducing depressive symptoms among community-dwelling older adults in the United States. Ten studies were identified for inclusion. Exercise interventions have positive effects on clinical depression and depressive symptoms among older adults. In addition, exercise interventions alleviated the depressive symptoms among older adults with a diagnosis of chronic disease. Future studies should include a randomized controlled trial with a larger sample, longitudinal design, and culturally sensitive intervention. For long-term benefits, incorporating motivational strategies into community exercise programs and collaborating with community health care providers are recommended to enhance the maintenance of exercise behavior among community-dwelling older adults. [Journal of Gerontological Nursing, 44(3), 31-38.].