Increases in muscular strength may increase sports performance, reduce injury risk, are associated with a plethora of health markers, as well as exerting positive psychological effects. Due to their efficiency and effectiveness in increasing total body muscular strength, multi-joint exercises like the powerlifts, i.e.: the squat (SQ), bench-press (BP) and deadlift (DL), are widely used by active individuals as well as athletes in the pursuit of increasing strength. To date, the concept of a minimum dose, i.e. “what is the minimum one needs to do to increase 1-repetition maximum (1RM) strength?” has not been directly examined in the literature, especially in the context of the powerlifts. This review aims to explore the current available evidence around the minimum effective training dose required to increase 1RM strength in trained individuals in an attempt to enhance the practical guidelines around resistance-training as well as provide active individuals, athletes and coaches with more flexibility when designing a training protocol.