Objective To gain insight on how exercise affects the outcomes of prostate cancer patientstreated with androgen deprivation therapy, specifically cancer-related fatigue (CRF) and quality of life(QoL).Methods Systematic searches for randomized clinical trials (RCTs) evaluating the effects of exerciseon CRF and QoL of prostate cancer patients receiving androgen deprivation therapy were carried out toidentify the eligible studies from EMBASE, PubMed and Cochrane library. Related data were extracted fromeligible studies and then subjected to Reviewer Manage 5.3 for analysis. Standardized mean differences (SMD)and its 95% confidence interval (CI) were calculated.[第一段]