Chronic lower-limb lymphoedema disrupts physical and mental health and requires labour-intensive therapies. This review synthesised evidence on the impact of exercise therapy on sufferer quality of life and symptom experience, concluding that exercise may improve strength, fitness, function, and decrease fatigue. It might also improve quality of life and subjective symptom scores, or at least have no negative impact. Existing studies are heterogenous in terms of size and exercise type, intensity, and frequency. Larger, more coordinated trials of longer duration are required in the future.