Background and aim: Extensive epidemiological evidence suggests that nonalcoholic fatty liver disease (NAFLD) is the primary chronic liver disease worldwide. However, some studies have showed conflicting results on the effects of probiotics and synbiotics supplementation. Therefore, we conducted ...

Background: The U.S. Department of Agriculture developed Dietary Guidelines for Americans, 2010, by taking into consideration evidence-based nutritional science, changes in the food supply and environmental influences. Conclusions: The 2010 guidelines emphasize the importance of maintaining ca...

Aim: To provide a systematic review and meta-analyses investigating the association between overweight/obesity as defined by Body Mass Index (BMI) and periodontal disease in terms of clinical periodontal outcomes. Materials and methods: A systematic search of the literature was conducted by tw...

Background: Vitamin K antagonists (VKAs) may have potential antitumor effects in prostate cancer. However, the findings ofobservational studies are inconsistent. The purpose of the present study was to estimate the quantitative association between VKAsuse and prostate cancer risk by combining the ...

Previous reviews explored weight loss-induced metabolic changes in overweight and obese adults with type 2 diabetes (T2D) but did not report on the impact on patient-reported outcomes (PROs). This systematic review investigated the effect of weight loss interventions on weight loss and PROs in ov...

Aims: To investigate the association of breastfeeding with all-cause, cardiovascular, and ischaemic heart disease mortality. Methods and results: A long-term follow-up of 4999 children originally surveyed from 1937 to 1939 was undertaken (Boyd Orr cohort). Four thousand three hundred and seven...

It has been suggested that breast milk may play a role in the prevention of certain childhood cancers. We undertook a systematic review of published studies investigating the association between breast-feeding and childhood cancers using Medline (1966 to June 2004), supplemented with auto alerts ...

Peking Union Medical College, Chinese Academy of Medical Sciences, Graduate School of Peking Union Medical College, Department of Orthopedics, China-Japan Friendship Hospital, China-Japan Friendship Institute of Clinical Medicine

The vitamin D receptor (VDR) can influence cancer susceptibility through binding to vitamin D. However, the previous studies were contradictory. Therefore this meta-analysis was conducted to clarify the association between VDR polymorphisms (BsmI, TaqI, FokI, and ApaI) and cancer risk. One hundre...

The present meta-analysis aimed to investigate fiber consumption and all-cause mortality, and cause-specific mortality. MEDLINE and web of science database were searched for cohort studies published from inception to August 2014. Studies were included if they provided a hazard ratio (HR) and corr...